20-30 Minutes
6-12 Months
Rejuran Polynucleotides is an advanced skin rejuvenation solution designed to repair, restore, and revitalise your complexion from within. Powered by biocompatible salmon DNA fragments, Rejuran stimulates cellular regeneration, enhances collagen and elastin production, and improves skin texture with results that can last up to 12 months.
Unlike dermal fillers or Botox, Rejuran works by healing the skin at a cellular level, effectively targeting fine lines, acne scars, dullness, and the effects of under-eye ageing. Its anti-inflammatory properties support tissue repair, improve hydration, and strengthen the skin barrier over time.
Book your initial consultation with us today to find out more about Rejuran Polynucleotides and how it can help you achieve more youthful, radiant skin.
Rejuran Polynucleotides are a regenerative treatment that harnesses the power of DNA fragments derived from salmon, chosen for their remarkable biocompatibility with human skin.
These polynucleotides are long chains of nucleotides, which are the essential building blocks of DNA. When introduced into the skin, they trigger natural healing processes by stimulating fibroblast activity, promoting collagen and elastin production, and repairing cellular damage at the DNA level.
Rejuran works from within, rather than masking concerns superficially. Its non-immunogenic formulation means it’s generally well tolerated, although temporary injection-site effects and other potential complications can occur.
Effectively target skin concerns from within for natural, long-lasting results.
Find out more about the unique Rejuran Polynucleotides formula and how they can benefit your skin.
Rejuran polynucleotides offer a wide range of skin-enhancing benefits by working at a cellular level to repair and regenerate tissue. They stimulate collagen and elastin production, improving skin firmness, elasticity, and overall texture. Over time, clients notice smoother, more radiant skin with reduced fine lines, pore size, and scarring.
In addition to anti-ageing effects, Rejuran supports deep hydration, strengthens the skin barrier, and promotes a brighter, more even skin tone. Its anti-inflammatory properties make it suitable for sensitive or compromised skin, while its natural composition ensures low risk of reaction and gradual, long-lasting results.
Key benefits include:
We recommend arriving with clean, makeup-free skin and avoiding any skincare products containing retinoids, exfoliants, or acids for at least 48 hours prior to your appointment.
It’s also advisable to minimise alcohol intake and avoid strenuous exercise on the day of treatment, as these may increase the risk of bruising. Please tell your practitioner about any medicines or supplements you take, including aspirin, ibuprofen or fish oil. Do not stop taking prescribed medication unless you have been advised to do so by the healthcare professional responsible for your care.
Staying well-hydrated and maintaining good skin health in the days leading up to your appointment can also further support the treatment’s effectiveness.
After your Rejuran Polynucleotide treatment, it’s normal to experience mild swelling, redness, or small bumps at the injection sites, these typically subside within 24 to 72 hours. Skin should be kept clean and well-hydrated using gentle products, and apply SPF 30+ daily to protect against UV damage. Avoid wearing makeup, exercising intensely, using saunas or steam rooms, and consuming alcohol for 48–72 hours post-treatment.
For optimal results, avoid touching or rubbing the treated area and drink plenty of water to support skin recovery.
We may also give you tailored aftercare instructions to follow. These will be advised during your consultation and after your treatment.
Polynucleotides can be used in combination with other aesthetic treatments for improved results that last longer:
Helps improve skin structure & elasticity while enhancing results from other skin rejuvenation treatments.
Rejuran Polynucleotides are derived from highly purified salmon DNA. This DNA is rich in PDRN (polydeoxyribonucleotide), a well-researched form of polynucleotide known for its powerful regenerative and healing properties. PDRN has been shown to support cellular repair, stimulate fibroblast activity, and enhance skin tissue regeneration.
Key Facts:
Number of Sessions |
Pricing |
| 1 Session | £270 |
| 2 Sessions | £520 |
| 3 Sessions | £770 |
| 4 Sessions | £1020 |
Number of Sessions |
Pricing |
| 1 Session | £250 |
| 2 Sessions | £480 |
| 3 Sessions | £710 |
| 4 Sessions | £940 |
Rejuran Polynucleotides are injectable skin boosters made from highly purified salmon DNA. These DNA fragments stimulate the skin’s natural healing process by promoting collagen and elastin production, repairing damaged tissue, and reducing inflammation. They work at a cellular level to restore skin health, improve texture, and enhance overall radiance.
Rejuran can be suitable for a wide range of skin types and tones, including sensitive skin. However, skin type alone does not determine whether treatment is suitable for you. During your consultation, we will consider your medical history, allergies, medicines, current skin condition and the area being treated before recommending Rejuran.
Rejuran is ideal for treating fine lines, dull or uneven skin tone, enlarged pores, acne scars, and general skin ageing. It’s also effective for improving hydration, elasticity, and under-eye concerns such as dark circles or crepey texture.
Rejuran is designed to improve skin quality gradually by supporting the skin’s natural regenerative processes. Dermal fillers primarily add or restore volume, while anti-wrinkle injections temporarily reduce movement in specific muscles. Rejuran does neither of these. Instead, it is used to improve concerns such as skin texture, hydration, elasticity and fine lines.
For best results, we recommend a course of 3 to 4 sessions spaced about 3 to 4 weeks apart. After the initial course, maintenance treatments every 6 to 12 months can help sustain the benefits.
Most of our clients begin to notice visible improvements in skin texture, hydration, and tone within 2 to 4 weeks after their first treatment. Results continue to develop over time as collagen production increases and skin regeneration takes place.
Downtime is minimal. Mild swelling, redness, or small bumps at the injection sites may appear but typically subside within 24 to 72 hours. You can usually return to normal activities shortly after treatment, following a few simple aftercare guidelines.
Discomfort is generally mild. A topical numbing cream is applied before the procedure to ensure comfort throughout. Clients may feel slight pressure or pinching during the injections, but the treatment is well tolerated by most people.
Rejuran can be used alongside other aesthetic and skin treatments, but the most appropriate combination and timing will depend on your skin, treatment area and goals. At Lumineux Aesthetics, we may recommend combining it with treatments such as microneedling or other skin rejuvenation procedures where appropriate. Your treatment plan will be discussed during consultation.
Results vary from person to person, but improvements following a course of Rejuran treatment may last around 6 to 12 months. Factors such as your skin condition, treatment area, number of sessions and individual response can all affect longevity. Maintenance treatment may be recommended to help sustain the results.
Rejuran may not be suitable if you are pregnant or breastfeeding, have an active infection or inflammation in the treatment area, or have certain medical conditions or allergies. You should also tell us about any medicines, supplements and known fish or salmon allergies. A full consultation is carried out before treatment to determine whether Rejuran is appropriate for you.
Common temporary effects after Rejuran injections can include redness, swelling, tenderness, bruising and small raised bumps at the injection sites. These usually settle within a few days. As with any injectable treatment, less common complications such as infection or an allergic reaction can occur. You will be given aftercare advice and information on when to contact the clinic if you have concerns.
Yes. Rejuran I is specifically formulated for the delicate under-eye area. It can be used to improve skin quality where concerns include fine lines, crepey texture and loss of elasticity. Whether it is appropriate for your under-eye concerns will be assessed during consultation, as not every cause of dark circles or under-eye ageing responds to the same treatment.
Book your Rejuran Polynucleotide treatment in Southampton at Lumineux Aesthetics. Our Rejuran Polynucleotide injections are administered by highly skilled and certified medical professionals, who will guide you through every step of the process.
Reach out to schedule a consultation and discover how our treatments can benefit you. We’re delighted to guide you in choosing the best procedures to reveal your inner beauty.
Arena Business Centre,
Threefield Ln,
Southampton,
SO14 3LP,
United Kingdom
Tuesday, Thursday & Friday: 10:30am – 8pm
Phone: 07720 305 368
Email: jacqui@lumineuxaesthetics.co.uk